Publications
2026
Pulavan N, Nenninger A, Mbuli J, Poklembova J & Dimitriu T (2026) Type of conjugative pili governs transfer efficiency in liquid and affects interpretation of transfer assays. bioRxiv https://www.biorxiv.org/content/10.64898/2026.04.01.715510v1
2025
Matthews AC, Lehtinen S & Dimitriu T (2025) Plasmid streamlining drives the extinction of antibiotic resistance plasmids under selection for horizontal transmission. PLoS Biology 23 (12) e3003564 https://doi.org/10.1371/journal.pbio.3003564
Shaw LP, Celis AP, Arroyo MA, Luo L, Dimitriu T & de la Cruz F (2025) The leading region of many conjugative plasmids is depleted in restriction-modification targets. bioRxiv 2025.04.03.647016
2024
Dimitriu T, Szczelkun MD, Westra ER (2024) Various plasmid strategies limit the effect of bacterial Restriction-Modification systems against conjugation. Nucleic Acids Research 52 (21) 12976-12986. https://doi.org/10.1093/nar/gkae896
Vos M, Buckling A, Kuijper B, Eyre-Walker A, Bontemps C, Leblond P & Dimitriu T (2024) Why do mobile genetic elements transfer DNA of their hosts ? Trends in Genetics 40 (11), 927-938. DOI: 10.1016/j.tig.2024.07.008
Relevant publications before 2024
Dimitriu T (2022) Evolution of horizontal transmission in antimicrobial resistance plasmids. Microbiology 168 (7), 001214. https://doi.org/10.1099/mic.0.001214
Dimitriu T, Kurilovich E, Lapinska U, Severinov K, Pagliara S, Szczelkin MD, Westra ER (2022) Bacteriostatic antibiotics promote CRISPR-Cas adaptive immunity by enabling increased spacer acquisition. Cell Host & Microbe 30 (1), 31-40.e5 https://doi.org/10.1016/j.chom.2021.11.014
Pursey E, Dimitriu T, Paganelli FL, Westra ER, van Houte S (2022) CRISPR-Cas is associated with fewer antibiotic resistance genes in bacterial pathogens. Phil Trans Roy Soc B 377 (1842), 20200464. https://doi.org/10.1098/rstb.2020.0464
Dimitriu T, Matthews AC and Buckling A (2021) Increased copy number couples the evolution of plasmid horizontal transmission and antibiotic resistance. Proceedings of the National Academy of Sciences 118 (31), e2107818118 https://doi.org/10.1073/pnas.2107818118
Dimitriu T, Szczelkun MD and Westra ER (2020) Evolutionary Ecology and Interplay of Prokaryotic Innate and Adaptive Immune Systems. Current Biology 30 (19), R1189-R1202. https://doi.org/10.1016/j.cub.2020.08.028
Dimitriu T, Marchant L, Buckling A and Raymond B (2019) Bacteria from natural populations transfer plasmids mostly towards their kin. Proceedings of the Royal Society B 286 (1905), 20191110. https://doi.org/10.1098/rspb.2019.1110
Dimitriu T, Misevic D, Lotton C, Brown SP, Lindner AB and Taddei F (2016) Indirect Fitness Benefits Enable the Spread of Host Genes Promoting Costly Transfer of Beneficial Plasmids. PLoS Biology 14(6):e1002478. https://doi.org/10.1371/journal.pbio.1002478
Dimitriu T, Lotton C, Bénard-Capelle J, Misevic D, Brown SP, Lindner AB and Taddei, F (2014) Genetic information transfer promotes cooperation in bacteria. Proceedings of the National Academy of Sciences 111 (30) 11103–11108. https://doi.org/10.1073/pnas.140684011
Banner photo: Prismes électriques, by Sonia Delaunay (1914)